Methylene Blue Powder, USP Grade
Methylene Blue Powder, USP Grade
- Third-Party Quality Tested
- USP Monograph Specifications
- Elemental Impurity Testing
- Lot-Specific Certificate of Analysis
- No Formaldehyde
- No Heavy Metals
ufcbio
Cat no. / M122965-1G
In stock
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Certificate of Analysis (COA) Available
Safety Data Sheet (SDS) Available
UFC BIO Methylene Blue Powder is a high-purity methylene blue hydrate manufactured and tested against established quality specifications.
Each production lot is evaluated for identity, assay, related substances, and applicable quality attributes. The material is tested against the applicable USP Methylene Blue monograph requirements, with lot-specific analytical results available through the Certificate of Analysis.
Methylene blue, also known as methylthioninium chloride, is a phenothiazine dye and oxidation-reduction compound used in a variety of analytical, laboratory, research, and technical applications.
UFC BIO Methylene Blue powder can be dissolved in water for further use.
Certificate of Analysis available by lot number. Safety Data Sheet available.
Product Properties
| Product | Methylene blue hydrate |
| Form | Powder |
| Quality | Tested to USP monograph |
| Packaging | Glass vial |
| Sizes | 1 g, 5 × 1 g |
Important Safety Information
- Methylene blue has known pharmacologic activity and may interact with certain medications.
- Individuals taking prescription or over-the-counter medications, particularly serotonergic medications, should discuss methylene blue with an appropriately qualified healthcare professional or pharmacist.
- Individuals with known or suspected G6PD deficiency should consult an appropriately qualified healthcare professional before considering use.
- Pregnant or breastfeeding individuals should consult an appropriately qualified healthcare professional.
- Keep out of reach of children.
- No dosing recommendation is provided.
How to Make 1% Methylene Blue Solution
- Add 1 gram of methylene blue powder to 100 milliliters of water to reconstitute. Shake well.
Methylene Blue Wholesale
UFC BIO provides Methylene Blue in wholesale and OEM packaging. Contact info@ufcbio.com to learn how we can meet your needs.
CAS Number 7220-79-3
| Test | Specification |
|---|---|
| Appearance | Dark green or blue crystalline powder having a bronze-like luster |
| Solubility (1% in water) | Clear blue solution |
| Assay (dry weight basis) | ≥ 97.0 to ≤ 103.0% |
| Loss on Drying (105 °C, > 3 h) | 8 – 24% |
| Identification Tests | |
| A: Infrared Spectrum | Conforms |
| B: Retention Time (RT) | Retention time of the principal peak corresponds to the reference standard |
| C: Identification of Chloride | Meets the requirements |
| Residue on Ignition | ≤ 0.15% |
| UV-Vis λmax, in 50% ethanol | 662 – 665 nm |
| Elemental Impurities | |
| Copper (Cu) | ≤ 200 ppm |
| Zinc (Zn) | ≤ 200 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Cadmium (Cd) | ≤ 1 ppm |
| Lead (Pb) | ≤ 5 ppm |
| Mercury (Hg) | ≤ 1 ppm |
| Organic Impurities | |
| Azure B | < 2.5% |
| Any unspecified impurity | ≤ 0.10% |
| Total impurities (excluding Azure B) | ≤ 0.50% |
| Bacterial Endotoxin | ≤ 2.5 EU/mL |
| Microbial Enumeration (TAMC) | < 1000 cfu/g |
| Yeast and Mold | < 100 cfu/g |
| Product Information | |
| Chemical Name | Methylene Blue / Methylthioninium Chloride |
| Form | Trihydrate |
| Molecular Formula | C₁₆H₁₈ClN₃S·3H₂O |
| Molecular Weight | 319.86 (anhydrous basis) |
| Storage Conditions | 4 °C to 25 °C (Ambient) |
| Product Codes (GTIN) | |
| 1 g | 00850072403052 |
| 5 g | 00850072403045 |
Refer to the lot-specific Certificate of Analysis for actual results and specifications.
The following independent scientific and medical publications provide background information on the chemistry, pharmacology, clinical history, and safety of methylene blue:
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Cellular and Molecular Actions of Methylene Blue in the Nervous System
Oz M, Lorke DE, Hasan M, Petroianu GA. Medical Research Reviews. 2011;31(1):93-117. DOI: 10.1002/med.20177.
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Methylene Blue: Revisited
Ginimuge PR, Jyothi SD. Journal of Anaesthesiology Clinical Pharmacology. 2010;26(4):517-520.
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Methylene Blue and Serotonin Toxicity: Inhibition of Monoamine Oxidase A (MAO A) Confirms a Theoretical Prediction
Ramsay RR, Dunford C, Gillman PK. British Journal of Pharmacology. 2007;152(6):946-951. DOI: 10.1038/sj.bjp.0707430.
-
Methylene Blue
Ostrovsky A, Afzal M. StatPearls. Updated January 2, 2026. This is a current NCBI clinical reference covering pharmacology, uses, contraindications, adverse effects, and interactions.
-
Ultimate Guide for Methylene Blue
Mark Sloan. May 14, 2021.
These references provide general scientific information and do not constitute dosing recommendations or claims regarding the intended use of UFC Bio Methylene Blue 1% Solution.
Shipping
Free standard ground shipping when your order includes $50 or more of UFC BIO products, shipped within the contiguous US (lower 48 states).
Returns
30-day returns within the contiguous US. Once we receive and inspect your return, we’ll issue a full refund within 3–5 business days.
Returns are not accepted more than 30 days after delivery unless an extension is approved.
Alaska, Hawaii, Puerto Rico & international
Orders shipping outside the contiguous US (including Canada) do not qualify for free shipping. Shipping costs are determined at checkout. If a shipping option isn’t available, please contact us at info@ufcbio.com.
Certificate of Analysis (COA)
Search for a Certificate of Analysis by entering the product’s Lot/Batch Number. You’ll find it on the product label after the word ‘Lot’ or ‘Batch’.
COA found. Opening the PDF in a new tab…
Safety Data Sheet (SDS)
Handling, storage and safety information for this product.
Download SDS (PDF) ↗- Choosing a selection results in a full page refresh.
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