Methylene Blue 1% Solution
Methylene Blue 1% Solution
- Made with high-purity, USP-grade methylene blue
- Lot-specific quality testing
- Certificate of Analysis available
- Safety Data Sheet available
- No Formaldehyde
- No Heavy Metals
- Manufactured in the USA
UFC BIO
Cat no. / MBS-USP1-100ML
In stock
Couldn't load pickup availability
Free Shipping Available
Certificate of Analysis (COA) Available
Safety Data Sheet (SDS) Available
Original Manufacturer
100% satisfaction guaranteed, read Our Promise
Manufactured in New York, Made in the USA
UFC BIO Methylene Blue 1% Solution is a standardized aqueous preparation manufactured using methylene blue raw material tested to applicable USP specifications and high-purity water, USP.
The product is manufactured under controlled conditions and each production lot is evaluated against established quality specifications. A lot-specific Certificate of Analysis is available.
Methylene blue, also known as methylthioninium chloride, is a phenothiazine compound with well-characterized oxidation-reduction and dye properties.
Each 100 mL bottle contains methylene blue at 1.0% w/v (10 mg/mL) in Water, USP, made and packaged in the USA.
Safety Data Sheet (SDS) and Certificate of Analysis (COA) available.
Product Information
| Chemical Name | Methylene blue |
| CAS Number | 122965-43-9 (7220-79-3) |
| Concentration | 1.0% w/v (10 mg/mL) |
| Assay | 1.00% ± 0.05% |
| Solvent | Water, USP |
| Appearance | Clear blue solution |
| Package Size | 100 mL |
| Storage | 4 °C to 25 °C |
| Catalog Number | MBS-USP1-100ML |
| Country of Origin | USA |
Important Safety Information
- Methylene blue has known pharmacologic activity and may interact with certain medications.
- Individuals taking prescription medications, particularly serotonergic medications, or individuals with known G6PD deficiency should consult an appropriately qualified healthcare professional before considering use.
- Pregnant or breastfeeding individuals should consult a healthcare professional before use.
- Keep out of reach of children.
- Review the Safety Data Sheet and product information before use.
Quality
UFC BIO evaluates each lot according to established product specifications. Testing may include:
- identity
- methylene blue concentration/assay
- UV/Visible spectral characteristics
- appearance
- selected elemental impurities
- other applicable quality attributes
Refer to the lot-specific Certificate of Analysis for actual results and specifications.
Common Laboratory Applications
- Biological staining of cells and tissues
- Microbiology staining
- Oxidation-reduction (redox) indicator
- Spectrophotometric reference work
- Teaching and demonstration laboratories
- Stock solution for further dilution
Intended Use
- UFC BIO Methylene Blue 1% Solution is manufactured as a standardized methylene blue solution.
- UFC BIO does not represent this product as intended to diagnose, treat, cure, mitigate, or prevent any disease.
- The suitability of methylene blue for an individual's intended use should be discussed with an appropriately qualified healthcare professional, particularly when other medications are being used.
Frequently Asked Questions
What is the concentration of this methylene blue solution?
The solution contains methylene blue at 1.0% w/v, which is 10 mg per mL. The assay specification is 1.00% ± 0.05%.
What is it made with?
It is made with methylene blue raw material tested to applicable USP specifications and Water, USP.
What is the CAS number for methylene blue?
The CAS number is 122965-43-9 for methylene blue hydrate. The anhydrous form is listed as 7220-79-3.
Which elemental impurities are tested?
The specification limits copper and zinc to ≤ 2.0 ppm, arsenic to ≤ 0.10 ppm, lead to ≤ 0.05 ppm, and cadmium and mercury to ≤ 0.02 ppm. See the Specification tab and the lot-specific COA for details.
Is a Certificate of Analysis available?
Yes. Each production lot has a lot-specific COA. Enter the Lot/Batch Number printed on the bottle in the COA search on the Documents tab.
Is an SDS available?
Yes. The Safety Data Sheet (SDS) is available on the Documents tab.
How should it be stored?
Store at 4 °C to 25 °C in the closed original bottle.
Where is it made?
UFC BIO Methylene Blue 1% Solution is made and packaged in the USA.
Is methylene blue also available as a powder?
Yes. Methylene Blue Powder, USP Grade is available in 1 g and 5 × 1 g sizes.
Methylene Blue Wholesale
Contact info@ufcbio.com to learn how UFCBIO can meet your wholesale and OEM packaging needs.
Explore more UFC BIO Dyes & Stains for laboratory and research applications.
CAS Number 122965-43-9 (7220-79-3)
| Test | Specification |
|---|---|
| Appearance – clarity, color, odor | Clear blue odorless solution |
| Assay (gravimetric) | 1.00% ± 0.05% |
| Identification (FTIR) | Conforms to spectrum |
| UV/Visible Spectrum | Conforms to control |
| Cations (elemental impurities) | |
| Copper (Cu) | ≤ 2.0 ppm |
| Zinc (Zn) | ≤ 2.0 ppm |
| Arsenic (As) | ≤ 0.10 ppm |
| Cadmium (Cd) | ≤ 0.02 ppm |
| Lead (Pb) | ≤ 0.05 ppm |
| Mercury (Hg) | ≤ 0.02 ppm |
Refer to the lot-specific Certificate of Analysis for actual results and specifications.
The following independent scientific and medical publications provide background information on the chemistry, pharmacology, clinical history, and safety of methylene blue:
-
Cellular and Molecular Actions of Methylene Blue in the Nervous System
Oz M, Lorke DE, Hasan M, Petroianu GA. Medical Research Reviews. 2011;31(1):93-117. DOI: 10.1002/med.20177.
-
Methylene Blue: Revisited
Ginimuge PR, Jyothi SD. Journal of Anaesthesiology Clinical Pharmacology. 2010;26(4):517-520.
-
Methylene Blue and Serotonin Toxicity: Inhibition of Monoamine Oxidase A (MAO A) Confirms a Theoretical Prediction
Ramsay RR, Dunford C, Gillman PK. British Journal of Pharmacology. 2007;152(6):946-951. DOI: 10.1038/sj.bjp.0707430.
-
Methylene Blue
Ostrovsky A, Afzal M. StatPearls. Updated January 2, 2026. This is a current NCBI clinical reference covering pharmacology, uses, contraindications, adverse effects, and interactions.
-
Ultimate Guide for Methylene Blue
Mark Sloan. May 14, 2021.
These references provide general scientific information and do not constitute dosing recommendations or claims regarding the intended use of UFC Bio Methylene Blue 1% Solution.
Shipping
Free standard ground shipping when your order includes $50 or more of UFC BIO products, shipped within the contiguous US (lower 48 states).
Returns
30-day returns within the contiguous US. Once we receive and inspect your return, we’ll issue a full refund within 3–5 business days.
Returns are not accepted more than 30 days after delivery unless an extension is approved.
Alaska, Hawaii, Puerto Rico & international
Orders shipping outside the contiguous US (including Canada) do not qualify for free shipping. Shipping costs are determined at checkout. If a shipping option isn’t available, please contact us at info@ufcbio.com.
Certificate of Analysis (COA)
Search for a Certificate of Analysis by entering the product’s Lot/Batch Number. You’ll find it on the product label after the word ‘Lot’ or ‘Batch’.
COA found. Opening the PDF in a new tab…
Safety Data Sheet (SDS)
Handling, storage and safety information for this product.
Download SDS (PDF) ↗Got it securely packaged. The dropper is great. Thank you for the swift delivery.
Very good
Checked the batch I received, COA, and put it in ChatGPT to confirm that it is the purest possible medical grade methylene blue. These guys are the real deal.
This product has the correct concentration without having to pay Amazon up pricing and the delivery was on time
Tried another brand that was supposedly 2% MB and it took 4 times as much to get same results as UFC Bio's 1%. This stuff is awesome!
Just wondering how long till this is back in stock?
100%
Met all my expectations
It's amazing! 2 drops is enough for us each day. The best and purest mblue out there! Ty for making this product affordable and easy to order!!
Great product and fast processing and delivery
I ordered 3 vials of methylene blue plus the $30 for expedited delivery over the weekend. It was shipped out on time as promised!
The best I have tried and I have tied a few. Thanks
Tried another brand that was supposedly 2% MB and it took 4 times as much to get same results as UFC Bio's 1%. This stuff is awesome!
👍👍👍👍
This 1% methyl blue is the best one I’ve tried. Trustworthy company!
You're the first brand of this product that i've tried, i'm not entirely sure about the general quality of the product, until I test out other brands. So far, it has stained my teeth and i excrete blue fluid, as for the energetic feeling, it is not there.
Delivery was prompt. Product as expected
the best Methylene Blue available
Seems to be a good product. I have had no issue with the dropper. That must be fixed. Good quality.
Too soon to develop a solid fact-based product analysis and I have nothing to compare it to. However. I have noticed more energy and overall clarity which I appreciate. I like the company and received the product fairly quick- quicker than most. I believe I can trust them and would definitely do business with them again.
Good quality and Good brand
I didn’t like it. I got other methane blew from Amazon. That does way better yours barely turns my pee green red blue. I felt nothing. I’m sorry I found you guys.
Searched high and low before I found this legitimate place to order MB. COA and serial numbers on each bottle with exp date. No BS like on Amazon.
We were introduced by a friend to use this
The dropper is the biggest problem. I ordered a different brand that I’ve used before due to the dropper and *I paid for 2/3 day delivery and it took 7 days. The half of the bottle I did take seemed like a good product compared to the 4 other brands I’ve used religiously for the last year and a half.
I think it's a quality product at a good price.
Good product, as advertised
Got here quickly. In about 4-5 days I noticed a difference in memory sharper and more clarity. Use twice a week mon and then Friday. Great product
I love this product. The dropper was cheap so I switched it to one that works well. But the product is good.
There are no dosage recommendations for the liquid. Where is that information available.?
Love it
Good Product and great service.